Which one of the following stages of chronic kidney disease corresponds to a glomerular filtration rate of 55 mL/min/1.73 m2?
3A
By the KDIGO CKD staging classification, GFR of 45-59 mL/min/1.73 m2 corresponds to Stage 3A (mild-to-moderate reduction). A GFR of 55 falls within this range, so the correct stage is 3A.
Which of the following statements are correct regarding anti-glomerular basement membrane disease?
1. It is a rare autoimmune disease which presents as rapidly progressive glomerulonephritis.
2. Antibodies are formed against $α3$ chain of type 4 collagen GBM.
3. The $α3$ chain is expressed in basement membrane of glomerulus and the retina.
4. The disease may be associated with retinal hemorrhage when it is known as Goodpasture syndrome.
Select the answer using the code given below :
Which of the following are poor prognostic indictators in glomerular disease?
1. Female sex
2. Hypertension
3. Persistent and severe proteinuria
4. Elevated creatinine levels at presentation
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Which of the following are indications for a renal biopsy?
1. Chronic kidney disease of uncertain etiology
2. Nephritic syndrome
3. Uncontrolled severe hypertension
4. Renal transplant dysfunction
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Which of the following drugs are effective in preventing uric acid nephropathy in patients receiving chemotherapy?
1. Probenecid
2. Forced saline diuresis
3. Rasburicase
4. Acetazolamide
Select the correct answer using the code given below.