Consider the following statements regarding Takotsubo cardiomyopathy: 1. There is acute right ventricular dysfunction characterized by dilatation of the right ventricular apex. 2. It can be precipitated by acute emotional stress and is frequently associated with an underlying neuro-psychiatric disorder. 3. Symptoms and ECG findings often mimic acute ST-elevation myocardial infarction. 4. Ventriculography shows normal left ventricle and apical ballooning of the right ventricle. Which of the statements given above are correct?
2 and 3
Takotsubo cardiomyopathy (stress cardiomyopathy) typically involves the LEFT ventricle, not right ventricle, so statements 1 and 4 are incorrect (they describe left ventricle findings but wrongly state right ventricle). It is classically precipitated by acute emotional/physical stress and associated with underlying psychiatric conditions (statement 2 correct), and presents with chest pain, ECG ST-elevation, and troponin rise mimicking STEMI despite normal coronaries (statement 3 correct). Hence 2 and 3 are correct.
A 60-year-old man comes to emergency with history of chest pain, which is acute onset. The ECG shows ST depression and T waves inversion. Cardiac biomarkers in blood are not elevated. What will be the appropriate management?