Consider the following statements regarding the murmur of Patent Ductus Arteriosus: 1. It is a continuous 'machinery' murmur. 2. There is a late diastolic accentuation. 3. It is maximal in the second left intercostal space below the clavicle. 4. With the development of Eisenmenger Syndrome, the murmur becomes louder and rumbling in character. Which of the statements given above is/are correct?
1 and 3
The classic PDA murmur is a continuous 'machinery' murmur (statement 1 correct) with late systolic accentuation (not late diastolic - statement 2 is incorrect as worded), heard maximally in the second left intercostal space, infraclavicular area (statement 3 correct). With development of Eisenmenger syndrome, the murmur actually diminishes or disappears as the shunt reverses and pulmonary pressures equalize, so statement 4 is incorrect. Hence statements 1 and 3 are correct.
A 60-year-old man comes to emergency with history of chest pain, which is acute onset. The ECG shows ST depression and T waves inversion. Cardiac biomarkers in blood are not elevated. What will be the appropriate management?