All Exams Test series for 1 year @ ₹349 only
Question

A middle aged diabetic male who has recurrent chest pain undergoes coronary artery angiogram. The following day, he develops haematuria, proteinuria and renal impairment. What is the most likely diagnosis?

The correct answer is
Atheroembolism

Understanding Atheroembolism Post-Angiogram

The patient's presentation suggests a complication following a coronary artery angiogram, particularly given his diabetic status, which implies underlying atherosclerosis.

  • Procedure: Coronary artery angiogram involves inserting a catheter into arteries, potentially dislodging atherosclerotic plaque.
  • Pathophysiology: Atheroembolism occurs when cholesterol crystals from atherosclerotic plaques break off, travel through the bloodstream, and lodge in small arteries.
  • Organ Involved: The kidneys are frequently affected due to their extensive small vessel network.
  • Clinical Triad: Atheroembolism affecting the kidneys characteristically presents with haematuria, proteinuria, and acute kidney injury (renal impairment).

Linking Symptoms to Atheroembolism

The observed symptoms of haematuria, proteinuria, and renal impairment developing the day after an angiogram in a diabetic patient are highly suggestive of atheroembolism. The procedure likely initiated the embolization of cholesterol debris into the renal microvasculature, leading to organ damage.

Evaluating Differential Diagnoses

  • Renal artery stenosis: Typically causes hypertension and chronic kidney disease, not acute symptoms post-angiogram.
  • Acute renal infarction: While possible, it usually presents with flank pain and is often a consequence of larger emboli; the diffuse symptoms favour atheroembolism.
  • Haemolytic Uraemic syndrome (HUS): Usually linked to infections or certain toxins, presenting with haemolytic anaemia and thrombocytopenia, which are not mentioned here.

Therefore, Atheroembolism is the most fitting diagnosis.

Was this answer helpful?

Important Questions from Renal Failure

  1. Which of the following are the renal complications of radiological investigations?
    1. Contrast nephrotoxicity
    2. Cholesterol atheroembolism
    3. Nephrogenic sclerosing fibrosis of skin
    Select the correct answer using the code given below:
  2. Which of the following are contraindications for renal biopsy?
    1. Normal size kidney
    2. Uncontrolled hypertension
    3. Solitary kidney
    4. Disordered coagulation
    Select the correct answer using the code given below:
  3. What is the target blood Hemoglobin level when treating anaemia in Stage-4 chronic kidney disease patient?
  4. Which one of the following complications of chronic kidney disease is observed in patients with low parathyroid hormone levels?
  5. All of the following statements about adult polycystic kidney disease are true, EXCEPT:
Need Expert Advice?

Start Your Preparation with Prepp Mobile App

Download the app from Google Play & App Store
Download the app from Google Play & App Store
Prepp Mobile App