Which one of the following hereditary tubulo-interstitial kidney diseases shows Autosomal Recessive pattern of inheritance?
Nephronophthisis
Nephronophthisis is the classic autosomal recessive hereditary tubulo-interstitial kidney disease and the most common genetic cause of end-stage renal disease in children. In contrast, medullary cystic kidney disease (types 1 and 2) and juvenile hyperuricaemic nephropathy (now grouped as ADTKD) are autosomal dominant.
Important Questions from Renal Failure
Which of the following statements are correct regarding anti-glomerular basement membrane disease?
1. It is a rare autoimmune disease which presents as rapidly progressive glomerulonephritis.
2. Antibodies are formed against $α3$ chain of type 4 collagen GBM.
3. The $α3$ chain is expressed in basement membrane of glomerulus and the retina.
4. The disease may be associated with retinal hemorrhage when it is known as Goodpasture syndrome.
Select the answer using the code given below :
Which of the following are poor prognostic indictators in glomerular disease?
1. Female sex
2. Hypertension
3. Persistent and severe proteinuria
4. Elevated creatinine levels at presentation
Select the correct answer using the code given below:
Which of the following are indications for a renal biopsy?
1. Chronic kidney disease of uncertain etiology
2. Nephritic syndrome
3. Uncontrolled severe hypertension
4. Renal transplant dysfunction
Select the correct answer using the code given below:
- Which of the following is the correct range of Glomerular Filtration Rate (GFR) for Stage 2 chronic kidney disease?
Which of the following drugs are effective in preventing uric acid nephropathy in patients receiving chemotherapy?
1. Probenecid
2. Forced saline diuresis
3. Rasburicase
4. Acetazolamide
Select the correct answer using the code given below.
