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Question

The '13C-urea breath test' and the 'faecal antigen test' are non-invasive techniques to diagnose infection with which one of the following?

This question was previously asked in
UPSC CMS 2026 Surgery, Gynaecology & Obstetrics, and PSM Question Paper (02-Aug-2026)
The correct answer is

Helicobacter pylori

The 13C-urea breath test relies on the urease activity of Helicobacter pylori, and the stool/faecal antigen test detects H. pylori antigens in stool. Both are standard non-invasive tests used to diagnose H. pylori infection, a major cause of peptic ulcer disease and gastritis.

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Important Questions from Peptic Ulcer Disease

  1. With regard to Helicobacter pylori eradication in peptic ulcer disease, consider the following statements: 

    1. Proton-pump inhibitor is taken with two antibiotics. 

    2. Treatment is prescribed for at least 7 days. 

    3. Treatment of Helicobacter pylori infection leads to vitamin B12 deficiency. 

    4. Patients requiring long-term NSAIDS should undergo Helicobacter pylori eradication therapy to reduce ulcer risk. 

    Which of the statements given above are correct?

  2. Which one of the following statements is correct with regard to peptic ulcer prophylaxis?
  3. The investigation of choice for early follow-up in patients treated for anti-$H.$ pylori drugs is
  4. The most common non-pancreatic site for tumour distribution in Zollinger-Ellison syndrome is
  5. Helicobacter pylori infection is associated with the development of which one of the following lymphoid malignancies?
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