Consider the following statements regarding 'Barrett's Oesophagus': 1. It is a pre-malignant condition. 2. The normal columnar mucosa of lower oesophagus is replaced by squamous cells. 3. It is an adaptive response to chronic gastro-oesophageal reflux. Which of the statements given above is/are correct?
1 and 3 only
Barrett's oesophagus is a pre-malignant condition (statement 1 correct) that develops as a metaplastic adaptive response to chronic gastro-oesophageal reflux disease (statement 3 correct). However, the change is the reverse of statement 2 — the normal stratified squamous epithelium of the lower oesophagus is replaced by columnar (intestinal-type) epithelium, not squamous replacing columnar. Hence statements 1 and 3 only are correct.
Important Questions from Peptic Ulcer Disease
With regard to Helicobacter pylori eradication in peptic ulcer disease, consider the following statements:
1. Proton-pump inhibitor is taken with two antibiotics.
2. Treatment is prescribed for at least 7 days.
3. Treatment of Helicobacter pylori infection leads to vitamin B12 deficiency.
4. Patients requiring long-term NSAIDS should undergo Helicobacter pylori eradication therapy to reduce ulcer risk.
Which of the statements given above are correct?
- Which one of the following statements is correct with regard to peptic ulcer prophylaxis?
- The investigation of choice for early follow-up in patients treated for anti-$H.$ pylori drugs is
- The most common non-pancreatic site for tumour distribution in Zollinger-Ellison syndrome is
- Helicobacter pylori infection is associated with the development of which one of the following lymphoid malignancies?
