A 30-year-old female with irritable bowel syndrome presents with predominant symptom of diarrhea. Which of the following will be helpful in her treatment? 1. Loperamide 2. Lactulose 3. Lubiprostone 4. Sorbitol Select the correct answer using the code given below:
1 only
Loperamide is an anti-motility agent used to control diarrhea and is appropriate for diarrhea-predominant IBS. Lactulose, Lubiprostone, and Sorbitol are all laxatives/osmotic agents used for constipation and would worsen diarrhea, making them inappropriate here. Hence only statement 1 is correct.
With regard to Helicobacter pylori eradication in peptic ulcer disease, consider the following statements:
1. Proton-pump inhibitor is taken with two antibiotics.
2. Treatment is prescribed for at least 7 days.
3. Treatment of Helicobacter pylori infection leads to vitamin B12 deficiency.
4. Patients requiring long-term NSAIDS should undergo Helicobacter pylori eradication therapy to reduce ulcer risk.
Which of the statements given above are correct?