Infiltration of the small-intestine mucosa with 'foamy' macrophages, which stain positive with Periodic Acid-Schiff (PAS) reagent, is a characteristic feature of which one of the following conditions?
Whipple's disease
Whipple's disease, caused by the bacterium Tropheryma whipplei, is classically characterized by infiltration of the small-intestinal lamina propria with PAS-positive foamy macrophages containing the bacillus. This is a key diagnostic histological finding distinguishing it from coeliac disease, tropical sprue, and radiation enteropathy.
Important Questions from Bacterial Infections
Which of the following are major criteria under the Jones Criteria for Acute Rheumatic Fever?
1. Chorea
2. Erythema Marginatum
3. Subcutaneous Nodules
4. Polyarthralgia
Select the correct answer using the code given below:
- Whipple's disease is characterized by the infiltration of small intestinal mucosa by 'foamy' macrophages. Which one of the following histological stains is characteristically used to stain them?
- A young male presented with recent onset urethral discharge and dysuria. On examination, the discharge was profuse and purulent. Microscopy of smears from the discharge revealed Gram-negative diplococci. What is the likely diagnosis?
- Cat-scratch disease is caused by infection of which of the following organisms?
Which of the following drugs is/are useful in the treatment of Listeria monocytogenes infection?
1. Ceftriaxone
2. Gentamicin
3. Ampicillin
4. Sulfamethoxazole
Select the correct answer using the code given below.
