Consider the following statements regarding gas gangrene: 1. It is caused by clostridial species, e.g., Clostridium perfringens. 2. It is characterized by a foul-smelling, painful wound containing serosanguineous discharge and gas bubbles. 3. It requires an aerobic environment and affects sites which are richly supplied with blood. 4. Radical amputation carries a high risk of advancing the infection to healthy tissue and is strictly contraindicated. Which of the statements given above are correct? (a) 1 and 2 (b) 2 and 3 (c) 3 and 4 (d) 1 and 4
1 and 2
Gas gangrene is caused by anaerobic clostridial species (notably Clostridium perfringens), classically presenting with a foul-smelling wound with serosanguineous discharge and gas bubbles (statements 1 and 2 correct). It requires an anaerobic (not aerobic) environment, typically in devitalized/poorly perfused tissue, and radical debridement/amputation is often life-saving, not contraindicated, making statements 3 and 4 incorrect.
Important Questions from Bacterial Infections
Which of the following are major criteria under the Jones Criteria for Acute Rheumatic Fever?
1. Chorea
2. Erythema Marginatum
3. Subcutaneous Nodules
4. Polyarthralgia
Select the correct answer using the code given below:
- Whipple's disease is characterized by the infiltration of small intestinal mucosa by 'foamy' macrophages. Which one of the following histological stains is characteristically used to stain them?
- A young male presented with recent onset urethral discharge and dysuria. On examination, the discharge was profuse and purulent. Microscopy of smears from the discharge revealed Gram-negative diplococci. What is the likely diagnosis?
- Cat-scratch disease is caused by infection of which of the following organisms?
Which of the following drugs is/are useful in the treatment of Listeria monocytogenes infection?
1. Ceftriaxone
2. Gentamicin
3. Ampicillin
4. Sulfamethoxazole
Select the correct answer using the code given below.
