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Question

A 35-year-old female presents with generalized muscle rigidity, difficulty in swallowing and laryngeal spasms for the past one week. She has developed trismus over the past 2 days and has a pulse rate of 130 beats/minute and a respiratory rate of 35 breaths/minute on presentation. She gives a history of getting her ears pierced from a roadside jewellery seller 2 weeks ago. What is the most probable diagnosis?

This question was previously asked in
UPSC CMS 2026 Surgery, Gynaecology & Obstetrics, and PSM Question Paper (02-Aug-2026)
The correct answer is

Tetanus

Trismus, generalized muscle rigidity, dysphagia, laryngeal spasm, and autonomic instability (tachycardia, tachypnea) following a contaminated puncture wound (unsterile ear piercing) are classic features of generalized tetanus caused by Clostridium tetani exotoxin.

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