Which of the following statements regarding Autoimmune Polyendocrine Syndromes (APS) is/are correct? 1. APS Type 1 is more common than APS Type 2. 2. APS Type 1 is inherited as an autosomal recessive condition. 3. APS Type 2 is inherited as an autosomal dominant condition. Select the correct answer using the code given below:
2 only
APS Type 2 (Schmidt syndrome) is far more common than APS Type 1, so statement 1 is false. APS Type 1 is caused by AIRE gene mutations and is inherited in an autosomal recessive manner (statement 2 true). APS Type 2 has a polygenic/HLA-associated inheritance pattern rather than simple autosomal dominant inheritance, so statement 3 is generally considered false. Hence only statement 2 is correct.
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With regard to the treatment of phaeochromocytoma, beta-blocker should never be given before alpha-blocker because it may cause:
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1. Octreotide
2. Lanreotide
3. Pasireotide
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Select the correct answer using the code given below:
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Important Questions from Adrenal Disorders
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List I
(disease)List II
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1. Polycystic ovarian syndrome
2. Congenital adrenal hyperplasia
3. Hypothyroidism
4. Ovarian tumour
Select the correct answer using the code given below:
