With regard to the treatment of phaeochromocytoma, beta-blocker should never be given before alpha-blocker because it may cause:
Paradoxical rise in blood pressure due to unopposed alpha-mediated vasoconstriction
In pheochromocytoma, catecholamine excess acts on both alpha and beta receptors. Blocking beta receptors first removes vasodilatory/compensatory beta-2 effects, leaving alpha-mediated vasoconstriction unopposed, causing a dangerous paradoxical rise in blood pressure (hypertensive crisis).
Which of the following is/are growth hormone receptor antagonist(s) indicated in the treatment of Acromegaly?
1. Octreotide
2. Lanreotide
3. Pasireotide
4. Pegvisomant
Select the correct answer using the code given below:
Liquorice misuse, by inhibiting 11 beta-hydroxysteroid dehydrogenase type 2 enzyme, can cause a condition which resembles the clinical features of:
Which of the following statements regarding Autoimmune Polyendocrine Syndromes (APS) is/are correct?
1. APS Type 1 is more common than APS Type 2.
2. APS Type 1 is inherited as an autosomal recessive condition.
3. APS Type 2 is inherited as an autosomal dominant condition.
Select the correct answer using the code given below:
| List I (disease) | List II (signs) |
| A. Conn syndrome | 1. Anosmia |
| B. Turner syndrome | 2. Tetany |
| C. Kallman syndrome | 3. Lymphoedema |
| D. Cushing syndrome | 4. Avascular necrosis of hip |