The classical presentation of an acute embolic occlusion in a limb includes all of the following, except
purple discoloration
The correct answer (the exception) is purple discoloration. Acute embolic limb occlusion, most often from atrial fibrillation with the embolus lodging at the common femoral bifurcation, classically gives the 6 Ps: Pain, Pallor, Pulselessness, Paraesthesia, Paralysis and Perishing cold (poikilothermia). The capillary bed empties abruptly, so the limb is marble-white, not purple. Fixed, non-blanching purple mottling means stagnant deoxygenated blood in thrombosed capillaries, that is irreversible ischaemia and impending gangrene, a late sign rather than the classical presentation.
Pain is sudden, severe and instantaneous in embolism. Pulselessness distal to the block is the key objective sign and localises the occlusion. Paralysis reflects ischaemic muscle and motor nerve and, with sensory loss, marks a threatened limb (Rutherford IIb) needing heparinisation and emergency Fogarty embolectomy within the 6 hour golden period.
Key point: Learn the 6 Ps with pallor, not purple; non-blanching purple mottling signals an already irreversibly ischaemic limb that may need primary amputation.
Consider the following statements regarding claudication:
1. It is a marker for silent coronary disease
2. Structured exercise program ( 2 hours per week for 3 months) leads to improvement in symptoms
3. Diabetes mellitus increases the risk and severity of claudication
4. Beta blockers may exacerbate claudication
Which of the above statements are correct?
Which of the following is NOT a symptom of atherosclerotic occlusive disease at the bifurcation of aorta (Leriche syndrome)?