Which of the following drugs have been used as part of mass drug administration (MDA) for elimination of lymphatic filariasis in some or more districts of India? 1. Albendazole 2. Diethylcarbamazine 3. Ivermectin 4. Metronidazole Select the correct answer using the code given below.
1, 2 and 3
The correct answer is 1, 2 and 3, that is Albendazole, Diethylcarbamazine (DEC) and Ivermectin. Under the National Programme for Elimination of Lymphatic Filariasis (now under NCVBDC), India conducts annual Mass Drug Administration (MDA) in endemic districts. The conventional regimen is DEC plus Albendazole once a year to the whole eligible population, excluding children under 2 years, pregnant women and the seriously ill. Since 2018, IDA or triple-drug therapy (Ivermectin + DEC + Albendazole) has been rolled out in selected districts, following WHO advice that IDA clears microfilaraemia far more effectively and shortens the number of MDA rounds needed to interrupt transmission.
Metronidazole (statement 4) is wrong; it is a nitroimidazole for anaerobic bacteria and protozoa such as amoebiasis, giardiasis and trichomoniasis, with no role in filariasis, so both '1 and 4 only' and '1, 2 and 4' fail. '2 and 3 only' is incomplete because it omits Albendazole, a component of both the two-drug and three-drug Indian regimens.
Key point: MDA equals DEC + Albendazole nationally, upgraded to IDA in selected districts. Doxycycline has an antiwolbachial role in individual treatment; Metronidazole is never used.
Important Questions from Infectious Disease Control & Prevention
As per the Open Vial Policy, partially used multidose vials of which of the following vaccines can be used over more than one immunization session?
1. BCG vaccine
2. DPT vaccine
3. Hepatitis B vaccine
4. Measles vaccine
Select the correct answer using the code given below.
Consider the following statements regarding dengue virus :
1. It has four distinct serotypes.
2. Infection with any one serotype confers lifelong immunity for that virus serotype.
3. Secondary infection with dengue serotype 2 leads to severe form of dengue.
Which of the statements given above are correct?
Consider the following statements regarding dengue :
1. The mosquito becomes infective after an extrinsic incubation period of 8-10 days.
2. Once it becomes infective, the mosquito remains infective for life.
3. The genital tract of the mosquito does not get infected.
Which of the statements given above are correct?
Consider the following statements about Kyasanur Forest Disease (KFD) :
1. It is transmitted by ticks.
2. It was originally called 'pig disease' because of the association with dead pigs.
3. It was first recognized in Karnataka State.
How many of the statements given above are correct?
- In countries with low levels of measles transmission, what should be the appropriate age for starting immuni-zation with measles-containing vaccine (MCV)?
