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Question

Consider the following statements regarding glucagon-like peptide-1 (GLP-1) and gastric inhibitory polypeptide (GIP):

1. GLP-1 is an incretin hormone.

2. GIP is an incretin hormone.

3. GLP-1 is released from gastrointestinal 'L-cells'.

4. GIP is released from gastrointestinal 'M-cells'.

Which of the statements given above are correct?

This question was previously asked in
UPSC CMS 2026 Surgery, Gynaecology & Obstetrics, and PSM Question Paper (02-Aug-2026)
The correct answer is

1, 2 and 3

GLP-1 and GIP are both incretin hormones (statements 1 and 2 true). GLP-1 is secreted by intestinal L-cells (statement 3 true). GIP, however, is secreted by K-cells of the duodenum/jejunum, not 'M-cells' (statement 4 is false). Hence 1, 2 and 3 are correct.

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