Consider the following statements regarding glucagon-like peptide-1 (GLP-1) and gastric inhibitory polypeptide (GIP): 1. GLP-1 is an incretin hormone. 2. GIP is an incretin hormone. 3. GLP-1 is released from gastrointestinal 'L-cells'. 4. GIP is released from gastrointestinal 'M-cells'. Which of the statements given above are correct?
1, 2 and 3
GLP-1 and GIP are both incretin hormones (statements 1 and 2 true). GLP-1 is secreted by intestinal L-cells (statement 3 true). GIP, however, is secreted by K-cells of the duodenum/jejunum, not 'M-cells' (statement 4 is false). Hence 1, 2 and 3 are correct.
Important Questions from Diabetes Mellitus
- A 52-year-old male diabetic presents with recurrent episodes of hypoglycemia. On examination, Pulse : 84 beats/minute, BP : 160/100 mm Hg, Chest and CVS examination unremarkable. Which of the following antihypertensive should be avoided in this patient ?
- Which of the following glucose lowering agent can be given as an injectable drug?
Which of the following findings are seen in Diabetic Retinopathy on fundus examination?
1. Microaneurysm
2. Dot and blot hemorrhage
3. Retinal thickening
4. Neovascularization
Select the correct answer using the code given below:
Which of the following statements are correct with regard to glucose homeostasis?
1. Insulin level rises postprandially.
2. Major portion of postprandial glucose is used by skeletal muscle.
3. Brain uses glucose in an insulin-dependent manner.
4. Glucagon is secreted during exercise.
Select the answer using the code given below :
Consider the following pancreatic hormones :
1. Insulin
2. Islet amyloid polypeptide or amylin
3. Glucagon
4. Somatostatin
Which of the above is/are secreted by beta cells of the pancreatic islets?
