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Question

Which one of the following drugs is not a secondary cause of weight gain?

This question was previously asked in
UPSC CMS 2026 Surgery, Gynaecology & Obstetrics, and PSM Question Paper (02-Aug-2026)
The correct answer is

Thyroxine

Sulphonylureas, glucocorticoids, and beta-blockers are well-known drug causes of weight gain. Thyroxine (levothyroxine) increases basal metabolic rate and is used to treat hypothyroidism-related weight gain; it is not itself a cause of weight gain.

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Important Questions from Diabetes Mellitus

  1. A 52-year-old male diabetic presents with recurrent episodes of hypoglycemia. On examination, Pulse : 84 beats/minute, BP : 160/100 mm Hg, Chest and CVS examination unremarkable. Which of the following antihypertensive should be avoided in this patient ?
  2. Which of the following glucose lowering agent can be given as an injectable drug?
  3. Which of the following findings are seen in Diabetic Retinopathy on fundus examination? 

    1. Microaneurysm 

    2. Dot and blot hemorrhage 

    3. Retinal thickening 

    4. Neovascularization 

    Select the correct answer using the code given below:

  4. Which of the following statements are correct with regard to glucose homeostasis? 

    1. Insulin level rises postprandially. 

    2. Major portion of postprandial glucose is used by skeletal muscle. 

    3. Brain uses glucose in an insulin-dependent manner. 

    4. Glucagon is secreted during exercise. 

    Select the answer using the code given below :

  5. Consider the following pancreatic hormones : 

    1. Insulin 

    2. Islet amyloid polypeptide or amylin 

    3. Glucagon 

    4. Somatostatin 

    Which of the above is/are secreted by beta cells of the pancreatic islets?

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