A prodrug is :
An inactive drug that is transformed in the body to an active metabolite
A prodrug is a pharmacologically inactive (or much less active) compound that is converted in the body, by enzymatic or chemical reactions, into the active drug.
Prodrugs are designed to improve absorption, stability, solubility, taste or targeting, or to reduce side effects. Examples: enalapril is hydrolysed by esterases to the active ACE inhibitor enalaprilat; levodopa is decarboxylated in the brain to dopamine.
A prototype is the representative drug against which others of its class are compared, which is a different idea; being the oldest member of a class says nothing about activation; and a drug stored in tissues and released slowly describes a depot or reservoir effect, not a prodrug.
Therefore a prodrug is an inactive compound transformed in the body into an active metabolite.
Hence, An inactive drug that is transformed in the body to an active metabolite.
Similar Questions
What major product is isolated from the following reaction :
Suggest most suitable conditions for the following selective conversion :
Complete the following reaction by suggesting the appropriate substrates (I & II) :
Predict the major product of the following reaction :
The major product formed in the following reaction is :
Predict the major product of the following reactions based on HSAB principle :
The major product of the following reaction is :
Predict the major product of the following reaction :
The major product of the following reaction is :
The major product of the following reaction is :
Important Questions from Chemistry in Everyday Life
Which of the following is a greenhouse gas?
I. Methane
II. Nitrous oxide
Which one of the following is used in soda-acid fire extinguishers?
The separation of two immiscible liquids can be done based on the difference in their_______.
Orange juice contains ______ acid due to which it tastes sour.
Impure water can be made pure
