Question
Which one of the following is true for Teriparatide for treatment of osteoporosis?
This question was previously asked in
UPSC CMS 2026 Surgery, Gynaecology & Obstetrics, and PSM Question Paper (02-Aug-2026)
The correct answer is
It is a fragment of human PTH and works by stimulating new bone formation.
Teriparatide is a recombinant fragment (amino acids 1-34) of human parathyroid hormone. Given intermittently (daily subcutaneous injection), it has an anabolic effect that stimulates new bone formation, unlike continuous PTH exposure which is catabolic. RANKL inhibition describes denosumab, and yearly dosing describes zoledronic acid, not teriparatide; it is generally not combined with bisphosphonates as this can blunt its anabolic effect.
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Important Questions from Osteoporosis
- Which of the following are correct with regard to osteoporosis ?
1. It does not cause symptoms until a fracture occurs
2. Vertebral fracture can present with loss of height, in absence of pain
3. Smoking is protective
4. It sometimes presents incidentally as radiological osteopenia
Select the correct answer using the code given below : - Use of which of the following drugs may result in osteoporosis ?
1. Phenytoin
2. Lithium
3. Methotrexate
4. Azathioprine
Select the correct answer using the code given below : - First line drug treatment to reduce fractures in osteoporosis is :
- Elevated serum alkaline phosphatase is seen in all except:
- Which one of the following is the most common site for a fracture associated with osteoporosis ?
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