Which one of the following is a type of Mitochondrial myopathy?
Myoclonic epilepsy with ragged red fibres
MERRF (Myoclonic Epilepsy with Ragged Red Fibres) is a classic mitochondrial disorder caused by mtDNA mutations (commonly MT-TK), producing ragged red fibres on muscle biopsy. The other options are genetic/idiopathic epilepsy syndromes unrelated to mitochondrial dysfunction.
Similar Questions
A 3-year-old boy presents to the emergency room with seizures. He has been receiving oral phenytoin since the age of 6 months and has a history of epileptic spasms despite therapy. Examination reveals some hypopigmented lesions over the chest. MRI brain shows subependymal nodules. Which one of the following is the best anti-epileptic drug for him after stabilization in the emergency room?
Which one of the following is a childhood onset epilepsy syndrome characterized by multiple seizure types, developmental delay and slow (< 3 Hz) spike-and-wave discharges on an electroencephalogram?
Important Questions from Epilepsy
- The rhythmic activity recorded on scalp by EEG in a normal awake adult lying quietly with eyes closed is:
Consider the following with regard to trigger factors for seizures :
1. Flickering lights
2. Recreational drug misuse
3. Non-compliance to treatment with antiepileptic drugs
4. Sleep deprivation
Which of the factors given above are correct?
Focal seizures may be associated with which of the following?
1. Jacksonian march
2. Todd's paralysis
3. Epilepsia partialis continua
Select the correct answer using the code given below.
- Typical absence seizures are characterized by
Match List I with List II and select the correct answer using the code given below the lists:
List I (Drugs for Epilepsy) List II (Side Effects - Dose Dependent) A. Sodium valproate 1. Raised liver enzymes B. Carbamazepine 2. Hirsutism C. Phenytoin 3. Hyperactivity D. Phenobarbitone 4. Drowsiness
