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Question

Which one of the following is a type of Mitochondrial myopathy?

This question was previously asked in
UPSC CMS 2026 Surgery, Gynaecology & Obstetrics, and PSM Question Paper (02-Aug-2026)
The correct answer is

Myoclonic epilepsy with ragged red fibres

MERRF (Myoclonic Epilepsy with Ragged Red Fibres) is a classic mitochondrial disorder caused by mtDNA mutations (commonly MT-TK), producing ragged red fibres on muscle biopsy. The other options are genetic/idiopathic epilepsy syndromes unrelated to mitochondrial dysfunction.

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Important Questions from Epilepsy

  1. Consider the following with regard to trigger factors for seizures : 

    1. Flickering lights 

    2. Recreational drug misuse 

    3. Non-compliance to treatment with antiepileptic drugs 

    4. Sleep deprivation 

    Which of the factors given above are correct?

  2. Focal seizures may be associated with which of the following? 

    1. Jacksonian march 

    2. Todd's paralysis 

    3. Epilepsia partialis continua 

    Select the correct answer using the code given below.

  3. Typical absence seizures are characterized by
  4. In a young epileptic woman wishing to use oral contraceptive agents, which of the following drugs is not an ideal agent?
  5. Which of the following is not useful in the management of status epilepticus?
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