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Question

A 10 year old child “blanks out” in class (e.g. stops talking midsentence and then continues as if nothing had happened). During spells there is slight quivering of lips. What is the most probable diagnosis?

The correct answer is
Absence seizure

Diagnosis of Childhood Neurological Symptoms

The question describes a 10-year-old child experiencing episodes of "blanks out" during class, stopping mid-sentence, and resuming conversation as if nothing occurred. These episodes are accompanied by slight quivering of the lips.

Evaluating Symptoms for Diagnosis

  • Absence Spells: The key symptom is the abrupt, brief interruption of consciousness or awareness, often described as "blanking out." This matches the child's behavior of stopping mid-sentence.
  • Motor Symptoms: Slight quivering of the lips is a common, subtle motor manifestation associated with certain seizure types.
  • Age Group: Absence seizures typically begin in childhood, often between ages 4 and 14.

Probable Diagnosis: Absence Seizure

Absence seizures (formerly known as petit mal epilepsy) are characterized by brief episodes of impaired awareness. The patient suddenly stops their activity, stares blankly, and may have subtle motor symptoms like lip-smacking, eye fluttering, or, as in this case, lip quivering. The episode lasts only a few seconds (typically less than 10-15 seconds), after which the child returns to normal activity, often unaware that anything happened.

Why Other Options Are Less Likely

  • Mutism: Typically involves a persistent inability or refusal to speak in specific situations or overall, not brief lapses in conversation.
  • Autism: Characterized by persistent deficits in social communication and interaction, alongside restricted and repetitive behaviors/interests. It does not typically present with isolated, brief staring spells.
  • Adjustment Disorder: A psychological condition arising in response to a stressor, manifesting as emotional or behavioral symptoms. It does not explain the specific neurological symptoms described.

Therefore, considering the characteristic symptoms of brief staring spells, cessation of activity, and subtle motor signs like lip quivering in a child, Absence seizure is the most probable diagnosis.

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Important Questions from Epilepsy

  1. Consider the following with regard to trigger factors for seizures : 

    1. Flickering lights 

    2. Recreational drug misuse 

    3. Non-compliance to treatment with antiepileptic drugs 

    4. Sleep deprivation 

    Which of the factors given above are correct?

  2. Focal seizures may be associated with which of the following? 

    1. Jacksonian march 

    2. Todd's paralysis 

    3. Epilepsia partialis continua 

    Select the correct answer using the code given below.

  3. Typical absence seizures are characterized by
  4. In a young epileptic woman wishing to use oral contraceptive agents, which of the following drugs is not an ideal agent?
  5. Which of the following is not useful in the management of status epilepticus?
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