Administration of immunoglobulins interferes with the response to live vaccines, except:
Oral typhoid vaccine
Passively administered antibodies (immunoglobulins) can neutralize parenterally given live viral vaccines like measles, mumps, and rubella before an adequate immune response develops. Oral live vaccines such as oral typhoid (Ty21a) and OPV act locally in the gut mucosa and are not neutralized by circulating immunoglobulins, so they are unaffected.
Similar Questions
A 4-year-old unimmunized HIV-positive child on antiretroviral therapy for the last 2 years and weighing 15 kg is brought for vaccination. His records reveal a recent CD4 count of 750/mm3, with no evidence of any opportunistic infections in the past. Which of the following statements are applicable to this child?
1. Recombinant Hepatitis B vaccine can be safely administered.
2. MMR vaccine is always contraindicated.
3. BCG may be administered if chest radiograph is normal.
4. IPV is preferred over OPV.
Select the correct answer using the code given below:
As per the National Immunization Schedule, PCV (Pneumococcal Conjugate Vaccine) is offered at:
Which one of the following vaccines is an exception to the principle "At least 4 weeks interval is needed between two doses of the same vaccine to ensure adequate immune response"?
Important Questions from Child Immunization
Which one of the following is the correct dose and route of administration of hepatitis B vaccine in children?
- Which one of the following statements is correct for approved acellular pertussis vaccine?
As per WHO recommendations which one of the following mumps vaccine strains should NOT be used in National Immunization Programme?
Which of the following is a contraindication for BCG vaccination in a newborn?
- Open vial policy applies to which one of the following vaccines?
