A 4-year-old unimmunized HIV-positive child on antiretroviral therapy for the last 2 years and weighing 15 kg is brought for vaccination. His records reveal a recent CD4 count of 750/mm3, with no evidence of any opportunistic infections in the past. Which of the following statements are applicable to this child? 1. Recombinant Hepatitis B vaccine can be safely administered. 2. MMR vaccine is always contraindicated. 3. BCG may be administered if chest radiograph is normal. 4. IPV is preferred over OPV. Select the correct answer using the code given below:
1 and 4
Recombinant Hepatitis B is an inactivated vaccine and is safe in HIV-infected children regardless of CD4 status (statement 1 true). MMR, a live vaccine, is NOT always contraindicated - it can be given if the child is not severely immunosuppressed (statement 2 false). BCG, being a live vaccine, is contraindicated once HIV infection is confirmed, irrespective of chest X-ray findings (statement 3 false). Since HIV-infected children are at risk of vaccine-associated paralytic polio, IPV (inactivated) is preferred over OPV (live) (statement 4 true). Hence 1 and 4 are correct.
Important Questions from Child Immunization
Which of the following are correct with regard to BCG vaccination?
1. It is a live-attenuated vaccine.
2. It is administered by intramuscular injection.
3. It is derived from Mycobacterium bovis.
4. It is highly immunogenic.
Select the answer using the code given below :
Consider the following statements :
1. Hepatitis B vaccine has reduced efficacy, if administered intramuscularly.
2. The maximum time allowed between reconstitution of MMR vaccine and use is 30 minutes.
3. Maternal antibodies do not interfere with cellular immune response to BCG vaccine.
4. DTwP is preferred to DTaP for primary immunization in most children.
Which of the statements given above are correct?
- Rotavirus vaccination is avoided during an episode of diarrhoea because
- The event related to vaccination which can be contraindication for the next vaccination of similar/identical type is
Which of the following events could be caused or precipitated by an active component of vaccine?
1. Anaphylaxis after measles vaccine
2. Encephalopathy after DPT vaccine
3. Adenitis following BCG vaccine
4. Gastroenteritis following MMR vaccine
Select the correct answer using the code given below.
