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Question

Which one of the following vaccines is an exception to the principle "At least 4 weeks interval is needed between two doses of the same vaccine to ensure adequate immune response"?

This question was previously asked in
UPSC CMS 2026 Surgery, Gynaecology & Obstetrics, and PSM Question Paper (02-Aug-2026)
The correct answer is

Rabies vaccine

The anti-rabies vaccine schedule (e.g., Essen regimen: days 0, 3, 7, 14, 28) does not follow the standard minimum 4-week interval rule applicable to most other multi-dose vaccines, since post-exposure prophylaxis requires a rapidly escalating immune response.

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Important Questions from Child Immunization

  1. Which of the following are correct with regard to BCG vaccination? 

    1. It is a live-attenuated vaccine. 

    2. It is administered by intramuscular injection. 

    3. It is derived from Mycobacterium bovis. 

    4. It is highly immunogenic. 

    Select the answer using the code given below :

  2. Consider the following statements : 

    1. Hepatitis B vaccine has reduced efficacy, if administered intramuscularly. 

    2. The maximum time allowed between reconstitution of MMR vaccine and use is 30 minutes. 

    3. Maternal antibodies do not interfere with cellular immune response to BCG vaccine. 

    4. DTwP is preferred to DTaP for primary immunization in most children. 

    Which of the statements given above are correct?

  3. Rotavirus vaccination is avoided during an episode of diarrhoea because
  4. The event related to vaccination which can be contraindication for the next vaccination of similar/identical type is
  5. Which of the following events could be caused or precipitated by an active component of vaccine? 

    1. Anaphylaxis after measles vaccine 

    2. Encephalopathy after DPT vaccine 

    3. Adenitis following BCG vaccine 

    4. Gastroenteritis following MMR vaccine 

    Select the correct answer using the code given below.

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