A farmer was suspected of some unknown substance poisoning, as he presented with bronchorrhoea, sweating and excessive salivation. Examination revealed bradycardia with bilateral miosis. Consider the following statements regarding his poisoning: 1. The symptoms represent Anti-Cholinergic Syndrome. 2. Activation of Acetylcholinesterase (AChE) enzyme is the underlying mechanism. 3. Intravenous Atropine should be given for treatment. Which of the statements given above is/are correct?
3 only
This presentation (bronchorrhoea, salivation, sweating, bradycardia, miosis) is the classic cholinergic (SLUDGE) syndrome of organophosphate poisoning, not an anticholinergic syndrome, so statement 1 is false. The mechanism is inhibition, not activation, of acetylcholinesterase, so statement 2 is false. IV Atropine is the correct first-line antidote, making only statement 3 correct.
Important Questions from Chemical Poisoning
Consider the following statements regarding organophosphate-induced delayed polyneuropathy (OPIDN) :
1. It is a rare complication and occurs 2 - 3 weeks after acute exposure.
2. It is a feature of poisoning with certain organophosphorus compounds such as triorthocresyl phosphate.
3. Inhibition of acetylcholinesterase causes motor polyneuropathy with no evidence of sensory loss.
4. There is no specific therapy although regular physiotherapy may limit deformity caused by muscle wasting.
Which of the statements given above are correct?
- The toxic effects of aluminium phosphide is due to the release of:
- Use of calcium carbide for the artificial ripening of fruits is banned but it is often reported to be illegally used. What is/are the likely health hazards of exposure to this chemical?
1. Permanent damage to the eyes
2. Pulmonary edema
3. Irritation of mouth, throat and nose
Select the correct answer using the codes given below: - Which of the following statements is correct regarding Malachite that is used as food adulterant?
Which of the following parts of the human body can be used as a sample/samples for the presence of mercury?
1. Blood
2. Hair
3. Nail
Select the correct answer using the code given below:
