Question
Which one of the following terms correctly denotes the mechanism and phenotypic changes that are not a result of variation in the underlying DNA sequence, but are caused by secondary modifications of DNA or histones in response to other heritable or environmental influences?
This question was previously asked in
UPSC CMS 2026 Surgery, Gynaecology & Obstetrics, and PSM Question Paper (02-Aug-2026)
The correct answer is
Epigenetics
Epigenetics refers to heritable changes in gene expression and phenotype caused by mechanisms such as DNA methylation and histone modification, without any change in the underlying DNA nucleotide sequence itself.
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Important Questions from Inflammation
A 24 year old man presents with acute onset shortness of breath with precordial chest pain. ECG reveals ST elevation with upward concavity and PR segment depression in lead V2 to V6 and reciprocal changes in lead aVR. The most likely diagnosis is
- Systemic Inflammatory Response Syndrome (SIRS) is characterized by all of the following EXCEPT:
- Which one of the following statements is correct?
- Multidrug resistant tuberculosis is defined as:
- Aortic stenosis is associated with:
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