Which of the following statements regarding Blood component transfusion related acute lung injury are correct? 1. Transfusion related acute lung injury (TRALI) usually manifests within 6 hours of transfusion. 2. Risk factors for TRALI include high titre anti-HLA class II antibodies in donor plasma. 3. TRALI due to cytokines or chemokines can occur even in the absence of HLA mediated interactions. Select the answer using the code given below:
1, 2 and 3
All three statements are correct: TRALI classically presents within 6 hours of transfusion, is caused by donor anti-leukocyte (anti-HLA class I/II or anti-neutrophil) antibodies reacting with recipient leukocytes, and a 'two-hit' non-antibody mediated (biologically active lipids/cytokines) mechanism can also cause TRALI independent of HLA interactions.
Important Questions from ICU Protocols
- Which of the following are the components of the SOFA (Sequential Organ Failure Assessment) ?
1. Serum bilirubin
2. Platelet count
3. Leucococyte count
4. Serum Creatinine
Select the correct answer using the code given below : - Which of the following are reversible causes of electromechanical dissociation seen in pulseless electrical activity ?
1. Pericardial tamponade
2. Pulmonary thrombo-embolism
3. Hyperthermia
4. Hypokalemia
Select the correct answer using the code given below : Which one of the following is NOT an appropriate criterion for diagnosis of Systemic Inflammatory Response Syndrome (SIRS)?
- All of the following are signs of Brain death EXCEPT:
- Biphasic defibrillation in case of ventricular fibrillation is first done with:
