The most significant "Supremacy clause" found in which Article of the United States constitution ?
Article VI
The Supremacy Clause of the United States Constitution is found in Article VI, Clause 2. It provides that the Constitution, and the laws of the United States made in pursuance thereof, and all treaties made under the authority of the United States, shall be the supreme law of the land, and the judges in every State shall be bound thereby. This clause has been repeatedly invoked, from McCulloch v. Maryland to the modern era, to strike down conflicting State legislation. Hence, the Supremacy Clause is in Article VI.
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