Deficiency of which of the following mineral(s) can lead to hypocalcemia by impairing the ability of the parathyroid gland to secrete parathyroid hormone? 1. Phosphate 2. Magnesium 3. Sodium 4. Potassium Select the correct answer using the code given below:
2 only
Severe hypomagnesemia impairs PTH secretion from the parathyroid gland (and causes end-organ PTH resistance), leading to functional hypoparathyroidism and hypocalcemia. Phosphate, sodium, and potassium deficiencies do not act through this PTH-secretion mechanism.
Sodium zirconium cyclosilicate and patiromer are commonly prescribed to chronic kidney disease patients because of their property of binding to which one of the following electrolytes?
Calcium resonium, which is used to treat hyperkalaemia over a short-term in chronic kidney disease, is associated with the development of which one of the following conditions?