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Question

Sodium zirconium cyclosilicate and patiromer are commonly prescribed to chronic kidney disease patients because of their property of binding to which one of the following electrolytes?

This question was previously asked in
UPSC CMS 2026 Surgery, Gynaecology & Obstetrics, and PSM Question Paper (02-Aug-2026)
The correct answer is

Potassium

Sodium zirconium cyclosilicate and patiromer are both non-absorbed potassium-binding agents used for the management of hyperkalaemia in CKD patients. They exchange other cations for potassium in the gastrointestinal tract, thereby lowering serum potassium.

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Important Questions from Electrolyte Imbalance

  1. A patient presents with history of 'bones, stones and abdominal groans' – due to generalised aches and pains and renal calculus colic. Which is the most discriminatory blood investigation?
  2. Which one of the following is the most appropriate initial treatment for management of severe hypercalcemia ?
  3. Which of the following are used in calculating the serum osmolality? 

    1. Serum sodium 

    2. Glucose 

    3. Calcium 

    4. Blood urea nitrogen 

    Select the correct answer using the code given below:

  4. Which of the following are used in the management of hyperkalemia? 

    1. 10% calcium gluconate intravenously 

    2. Regular insulin and intravenous glucose 

    3. Nebulized ipratropium bromide 

    4. Intravenous sodium bicarbonate 

    Select the correct answer using the code given below:

  5. Nebulized salbutamol is used in the management of which of the following electrolyte abnormality?
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