A patient with a history of chronic smoking presented with breathlessness for the last one year. On examination, there were bilateral rhonchi in the chest. The Chest X-ray was suggestive of hyper-inflated lung field. Which of the following parameters of the pulmonary function test are consistent with the diagnosis of chronic obstructive pulmonary disease in this case? 1. Decreased FEV1 2. Increased diffusion capacity 3. Increased residual volume 4. Decreased peak expiratory flow rate Select the correct answer using the code given below:
1, 3 and 4
COPD is characterized by decreased FEV1 due to airflow obstruction, increased residual volume due to air trapping, and decreased peak expiratory flow rate. Diffusion capacity (DLCO) is typically decreased (especially in emphysema-predominant COPD), not increased, making statement 2 incorrect. Hence statements 1, 3 and 4 are correct.