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Question

A 6-year-old boy is brought with complaints of involuntary, non-rhythmic, jerky movements of upper limbs and snorting sounds, noticed for the past 12 months. His MRI brain and EEG are normal. The child was mocked at by classmates in school and he stopped attending classes for the past 6 months. His ASLO titres and serum ceruloplasmin are non-contributory. The ideal therapy would be a trial of:

This question was previously asked in
UPSC CMS 2026 Surgery, Gynaecology & Obstetrics, and PSM Question Paper (02-Aug-2026)
The correct answer is

Oral Clonidine

Chronic motor tics with a vocal component (snorting), normal MRI/EEG, and exclusion of Sydenham chorea (normal ASLO) and Wilson disease (normal ceruloplasmin) point to Tourette syndrome/chronic tic disorder. For mild-to-moderate tics, especially with psychosocial impact, alpha-2 agonists such as oral clonidine are first-line pharmacotherapy, reserving antipsychotics like olanzapine for severe, refractory tics.

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Important Questions from Autism and Counselling

  1. Which of the following genetic causes are commonly associated with autism spectrum disorders? 

    1. Angelman syndrome 

    2. Fragile X syndrome 

    3. Tuberous sclerosis 

    4. Williams syndrome 

    Select the correct answer using the code given below.

  2. A 3-year-old boy presents with parental concerns regarding delayed development, especially speech. On observation, the clinician notes decreased eye contact, inattentiveness, unresponsive to being called and toe walking. What is the most likely diagnosis ?
  3. Atomoxetine is prescribed to children with Autism Spectrum Disorder to control symptoms of :
  4. A 3-year old boy is brought with complaints of staying aloof. He also has delayed speech. Rest of the developmental milestones were attained normally. The most likely diagnosis is:

  5. Which of the following drugs is NOT included in the management of Attention Deficit Hyperactivity disorder?

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