A 12-year-old boy is brought to the emergency in an unconscious state with a history of shallow breathing and increasing drowsiness noticed for two hours. He is noticed to have a dry mouth, cold extremities, is limp and has pin point pupils. The emergency physician suspects poisoning. Which one of the following antidotes should be administered?
Naloxone
Pinpoint pupils, respiratory depression (shallow breathing), CNS depression (drowsiness progressing to unconsciousness), and limp/hypotonic state constitute the classic opioid toxidrome. Naloxone is the specific opioid receptor antagonist antidote used to reverse these effects.
| Urine colour | Possible causative agent in a child with suspected poisoning |
| 1. Pink | - Cephalosporin |
| 2. Brown | - Chloroquine |
| 3. Greenish blue | - Phenazopyridine |
| 4. Red-orange | - Amitriptyline |
An 8 year old child has consumed a few tablets of a drug that were being taken by his motheron a regular basis. Following this the child develops gastric necrosis, acidosis, shock and hepatic necrosis. Which is the most likely drug?