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Question

An 8 year old child has consumed a few tablets of a drug that were being taken by his motheron a regular basis. Following this the child develops gastric necrosis, acidosis, shock and hepatic necrosis. Which is the most likely drug?

The correct answer is
Iron

Identifying the Toxic Drug Based on Symptoms

The question describes a scenario where an 8-year-old child ingested several tablets of a medication, leading to severe symptoms including gastric necrosis, acidosis, shock, and hepatic necrosis. We need to identify the most likely drug responsible.

Analyzing Symptoms of Drug Toxicity

  • Gastric Necrosis: Severe irritation and damage to the stomach lining.
  • Acidosis: A condition where there is too much acid in the body fluids.
  • Shock: A life-threatening condition due to insufficient blood flow.
  • Hepatic Necrosis: Death of liver cells.

Evaluating Medication Options

  • Multivitamins: Generally safe in moderate overdose; unlikely to cause such severe, specific toxicity.
  • Calcium Carbonate: Overdose can cause hypercalcemia and GI upset, but not typically necrosis or shock.
  • Folic Acid: Very low toxicity; overdose symptoms are rare and mild.
  • Iron: Iron supplements are well-known to be highly toxic in overdose, especially in children. The symptoms described—severe gastrointestinal distress (leading to necrosis), metabolic acidosis, cardiovascular collapse (shock), and liver damage (hepatic necrosis)—are classic signs of acute iron poisoning.

Conclusion on Most Likely Drug

Based on the severe symptoms of gastric necrosis, acidosis, shock, and hepatic necrosis, iron overdose is the most probable cause.

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Important Questions from Childhood Injuries and Poisoning

  1. In a child with acute organophosphorus poisoning, which one of the following drugs will act as anti-sialogogue and peripheral parasympatholytic agent?

  2. Gastric lavage is contraindicated in which of the following?
    1. Corrosive poisoning
    2. Organophosphorus poisoning
    3. Iron intoxication
    4. Turpentine oil ingestion
    Select the correct answer using the codes given below:
  3. In which one of the following age groups is the highest rate of drowning observed, worldwide?

  4. Which one of the following is used to estimate the surface area of burn injuries in children less than 15 years of age?
  5. A 4-year-old boy presents with ingestion of many tablets of salicylate. Which one of the following complications is he likely to develop?
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