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Question

Which one of the following can be classically elicited in a patient of Staphylococcal scalded skin syndrome?

This question was previously asked in
UPSC CMS 2026 Surgery, Gynaecology & Obstetrics, and PSM Question Paper (02-Aug-2026)
The correct answer is

Nikolsky sign

Staphylococcal scalded skin syndrome is caused by exfoliative toxin-producing S. aureus that cleaves desmoglein-1, causing superficial epidermal separation elicited as a positive Nikolsky sign (lateral pressure causing skin sloughing).

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Important Questions from Skin Infections

  1. Type-2 necrotizing fasciitis is caused by
  2. Tinea versicolor is caused by:
  3. Herald patch followed by rash is characteristic of:
  4. Consider the following statements: 

    1. Boils/suppurative lesions around the nose must be promptly treated with antibiotics. 

    2. Suppurative lesions around the nose lead to cavernous sinus thrombosis. 

    Which of the statements given above is/are correct?

  5. Match List I with List II

    List I (Physical Sign)List II (Medical Condition)
    A. Koebner phenomenon 1. Lepra reaction
    B. Erytdema nodosum2. Pemphigus vulgaris
    C. Erytdema multiforme3. Stevens-Johnson syndrome
    D. Nikolsky's sign4. Psoriasis
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