The typical ulcer as shown in the following diagram is seen in
tuberculosis
The correct answer is tuberculosis. The diagram shows an undermined (overhanging) edge, where the skin edge projects over a wider cavity so the base is broader than the surface opening. This happens when subcutaneous tissue is destroyed faster than the overlying skin, the classical behaviour of a tuberculous ulcer (and of an amoebic ulcer). Tuberculous ulcers are shallow with a pale wash-leather floor, thin bluish undermined edges and scanty seropurulent discharge, often over the neck from a collar-stud abscess of cervical nodes, caused by Mycobacterium tuberculosis. Biopsy shows caseating epithelioid granulomas; treatment is antitubercular therapy.
Syphilitic gummatous ulcers have a punched-out vertical edge. Squamous cell carcinoma gives an everted, rolled-out edge as proliferating tumour heaps over normal skin. Basal cell carcinoma (rodent ulcer) gives a rolled-in, beaded, pearly edge with telangiectasia.
Key point: Ulcer edges are a favourite one-liner: undermined = tuberculous, punched-out = syphilitic or trophic, everted = squamous carcinoma, beaded/rolled = basal cell carcinoma, sloping = healing.