The human protein obtained from transgenic animals used to treat emphysema is
α - 1 antitrypsin
Transgenic animals are animals whose DNA has been manipulated to possess and express an extra, foreign gene. NCERT notes that they are used to produce useful biological products by introducing into them the portion of DNA that codes for a particular product, such as human protein α-1-antitrypsin used to treat emphysema.
Emphysema is a chronic disorder in which the alveolar walls are damaged, reducing the respiratory surface. α-1-antitrypsin is a protease inhibitor that protects lung tissue from destruction, and its human form produced by transgenic animals is used in treating the disease.
Insulin is used to treat diabetes and was produced in E. coli through recombinant DNA technology by Eli Lilly. α-Lactalbumin is the human protein present in the enriched milk of the transgenic cow Rosie (2.4 grams per litre), a nutritionally more balanced product for human babies, not an emphysema treatment, and β-lactalbumin has no role in treating emphysema.
α - 1 antitrypsin option is correct.
Similar Questions
Given below are two statements
Statement I: Adenosine deaminase is crucial for the immune system to function.
Statement II: Adenosine deaminase deficiency can be cured only by bone marrow transplantation.
In the light of the above statements, choose the correct answer from the options given below.
Given below are the sequence of events in the production of human insulin by Eli Lilly.
a) Preparation of two DNA sequences corresponding to chain A and B of human insulin.
b) Production of chain A and B separately.
c) Introduction of chains in plasmids of E.coli.
d) Extraction of chain A and B combining them by creating disulphide bonds.
Choose the correct sequence of events.
Match List I with List II
List I List II a) Visualization of DNA in gel electrophoresis i) Chitinase b) Precipitation of DNA ii) Lysozyme c) Breaking of cell wall of bacteria iii) Chilled ethanol d) Breaking of cell wall of fungus iv) Ethidium bromide Codes:
Given below are two statements.
Statement I: Restriction enzyme BamHI has its recognition site in tetR region of pBR322.
Statement II: E.coli having pBR322 with a desired DNA if inserted at BamHI site can grow in medium containing tetracycline.
In the light of the above statements, choose the correct answer from the options given below.
Technique to alter the chemistry of genetic materials, DNA and RNA, to introduce these into host organism and change the phenotype of the host is
Important Questions from Biotechnology
- Insertion of a foreign DNA at BamHI site in an E. coli cloning vector pBR322 results in the loss of antibiotic resistance towards :
- Which of the following statements are not true regarding restriction endonucleases ?
A. They are called molecular scissors.
B. These are the enzymes responsible for restricting the growth of bacteriophages in E. coli.
C. They cut the DNA only at the centre of the palindromic sites.
D. They remove nucleotides only from the ends of DNA fragments.
E. They recognise specific palindromic base-pair sequences.
Choose the correct answer from the options given below : - Which of the following statements are correct with respect to DNA separation, isolation and visualization ?
A. The cutting of DNA is done by molecular scissors.
B. The DNA fragments separate according to their size in an agarose gel, upon electrophoresis.
C. The separated DNA fragments can be seen without staining when exposed to UV light.
D. The separated DNA fragments, when stained with ethidium bromide, can be seen in visible light.
Choose the correct answer from the options given below : - Match List I with List II :
List I List II A. Genetically modified organism I. Agrobacterium tumefaciens B. Thermostable DNA polymerase II. Bt cotton C. Ti plasmid III. Thermus aquaticus D. pBR322 IV. Escherichia coli
Choose the correct answer from the options given below : - Identify the correct sequence of steps in each cycle of Polymerase Chain Reaction :
