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Question

The disease rickets develops in children due to the deficiency of:

This question was previously asked in
CDS I 2022 English Previous Year Paper (10-April-2022)
The correct answer is

Vitamin D

Understanding Rickets and Vitamin Deficiency

Rickets is a condition that affects bone development in children. It causes the bones to become soft and weak, which can lead to bone deformities. Understanding the cause of rickets is crucial for prevention and treatment.

The Role of Vitamin D in Bone Health

Our bodies need certain vitamins and minerals to build and maintain strong bones. Two very important ones are calcium and phosphorus. Vitamin D plays a key role in helping the body absorb calcium and phosphorus from the food we eat. When there isn't enough Vitamin D, the body cannot absorb these minerals properly, even if they are present in the diet.

Think of Vitamin D as the helper that allows calcium and phosphorus to get from your digestive system into your bloodstream and then to your bones. Without enough Vitamin D, this process is inefficient.

Rickets: The Result of Vitamin D Deficiency

Because Vitamin D is essential for absorbing the building blocks of bone (calcium and phosphorus), a deficiency in Vitamin D directly impacts bone strength and structure in growing children. When calcium and phosphorus levels in the blood are too low due to Vitamin D deficiency, the minerals cannot be deposited properly into the growing bones. This causes the bones to soften, weaken, and potentially bend or deform over time, leading to the condition known as rickets.

Therefore, the disease rickets develops in children due to the deficiency of Vitamin D.

Comparing Vitamins and Their Deficiencies

Let's briefly look at the other options provided and the diseases associated with their deficiencies:

Vitamin Main Role Deficiency Disease
Vitamin C (Ascorbic Acid) Important for collagen formation, immune function, antioxidant Scurvy (weakness, anemia, gum disease, skin problems)
Vitamin D (Calciferol) Helps absorb calcium and phosphorus, crucial for bone health Rickets (in children), Osteomalacia (in adults)
Vitamin A (Retinol) Essential for vision, immune function, cell growth Night blindness, dry eye (xerophthalmia), increased infection risk
Vitamin B complex (e.g., B1, B2, B3, B12) Involved in metabolism, nerve function, blood cell formation Various conditions like Beriberi (B1), Pellagra (B3), Megaloblastic Anemia (B12, Folate)

From the table, it is clear that rickets is specifically linked to Vitamin D deficiency.

Revision Table: Rickets & Vitamin D

Key Concept Explanation
What is Rickets? A childhood bone disease causing soft, weak, and deformed bones.
Primary Cause of Rickets Deficiency of Vitamin D.
Vitamin D's Function Helps the body absorb calcium and phosphorus for bone mineralization.
Consequence of Deficiency Poor absorption of calcium and phosphorus leads to insufficient bone hardening.

Additional Information on Vitamin D and Rickets

Sources of Vitamin D:

  • Sunlight exposure (skin produces Vitamin D when exposed to UVB rays)
  • Certain foods like fatty fish (salmon, mackerel), fortified milk, fortified cereals, fortified orange juice, eggs
  • Vitamin D supplements

Risk Factors for Rickets:

  • Limited sunlight exposure (living in higher latitudes, using sunscreen heavily, spending most time indoors)
  • Darker skin pigmentation (skin produces less Vitamin D from sunlight)
  • Exclusive breastfeeding without Vitamin D supplementation (human milk is not high in Vitamin D)
  • Conditions affecting nutrient absorption (e.g., Celiac disease, Cystic Fibrosis)
  • Certain medications

Preventing rickets involves ensuring children get enough Vitamin D through a combination of safe sun exposure, diet, and supplementation if needed, especially for at-risk infants and children.

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