Sequence the following stages of cellular respiration: 1. Electron Transport Chain 2. Glycolysis 3. Krebs Cycle 4. Pyruvate Oxidation
2 → 4 → 3 → 1
Aerobic cellular respiration breaks down glucose in a fixed order of stages.
Glycolysis (2) comes first: in the cytoplasm, one glucose molecule is split into two molecules of pyruvate, with a small net gain of ATP and NADH.
Pyruvate Oxidation (4) follows: pyruvate enters the mitochondrion and is converted into acetyl-CoA, releasing CO2 (the link reaction).
Krebs Cycle (3) is next: acetyl-CoA is oxidised in the mitochondrial matrix, producing CO2, NADH, FADH2 and some ATP.
Electron Transport Chain (1) is last: on the inner mitochondrial membrane, NADH and FADH2 pass electrons to oxygen, and most of the ATP is made by oxidative phosphorylation.
Hence, the correct sequence is 2 → 4 → 3 → 1 (Glycolysis → Pyruvate Oxidation → Krebs Cycle → Electron Transport Chain).
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