What distinguishes rough ER (RER) from smooth ER (SER)?
Presence of ribosomes on RER, absence on SER
Correct Answer: Presence of ribosomes on RER, absence on SER
Differences between RER and SER:
| Feature | RER | SER |
|---|---|---|
| Ribosomes | Present (studded on surface) | Absent |
| Appearance | Rough/granular | Smooth |
| Function | Protein synthesis and processing | Lipid and steroid synthesis; detoxification |
The ribosomes on RER give it the 'rough' appearance. Both RER and SER have membranes, are involved in various cellular functions, and both are associated with proteins to some extent — ribosome presence/absence remains the true distinguishing feature.
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