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Question

The smooth endoplasmic reticulum (SER) helps in the manufacture of ___________.

This question was previously asked in
RRB Group D 2024 Question Paper PDF (21-Dec-2025) (Shift 2)
The correct answer is

lipids (fats)

The smooth endoplasmic reticulum (SER) lacks ribosomes on its surface, which gives it a smooth appearance. Its main job is the synthesis of lipids (fats), including phospholipids and steroids; in liver cells it also helps detoxify drugs and poisons.

Proteins are made by ribosomes, which sit on the rough endoplasmic reticulum (RER), so protein manufacture is the function of the RER, not the SER. DNA is synthesised (replicated) in the nucleus, not on the ER. Starch is a plant storage carbohydrate made and stored in plastids such as chloroplasts and amyloplasts, not in the SER.

Hence, the smooth endoplasmic reticulum helps in the manufacture of lipids (fats).

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