A. Tetracycline inhibits protein synthesis through interference with the binding of aminoacyl-tRNA to 30S subunit of ribosome
B. Chloramphenicol inhibits protein synthesis by combining with the 50S subunit of ribosome
C. Erythromycin inhibits protein synthesis by binding on the 30S subunit of ribosome
D. Streptomycin inhibits protein synthesis by combining with 30S subunit of ribosome
Choose the correct answer from the options given below:
Antibiotic Mechanisms on Protein Synthesis
This question asks to identify the true statements regarding the mechanisms of action of specific antibiotics on bacterial protein synthesis.
Mechanism Analysis
Let's analyze each statement:
- Statement A (Tetracycline): Tetracyclines bind to the 30S ribosomal subunit and prevent the attachment of aminoacyl-tRNA to the mRNA-ribosome complex. This statement is True.
- Statement B (Chloramphenicol): Chloramphenicol binds to the 50S ribosomal subunit, inhibiting peptidyl transferase activity and blocking peptide bond formation. This statement is True.
- Statement C (Erythromycin): Erythromycin binds to the 50S ribosomal subunit and inhibits the translocation step of protein synthesis. The statement incorrectly claims it binds to the 30S subunit. This statement is False.
- Statement D (Streptomycin): Streptomycin, an aminoglycoside, binds to the 30S ribosomal subunit. It interferes with the initiation complex formation and causes misreading of the mRNA codons. This statement is True.
Conclusion
Based on the analysis, statements A, B, and D are true. Statement C is false.
Therefore, the correct combination is A, B and D Only.
This corresponds to Option 3.
Similar Questions
- In Polymerase Chain Reaction (PCR) primers are used to provide:
- To detect specific proteins in a sample we use:
- The most commonly used stain for visualising/observing the DNA fragments is:
- The target sequence in a DNA can be determined/ identified in Southern blotting by:
- R$_f$ value depends on:
- Barr body is an example of:
Repeated sequence TTAGGC in humans is present at :
AATCCG- The attachment site for microtubules that separates chromosomes during cell division:
- The genetic material of a prokaryotic cell is present in:
- During denaturation which bonds in protein structure are NOT broken:
Important Questions from Mixed Topic (CUET PG)
- Who was the founder of Bolshevik Communist party?
- What is the key guide to statecraft in the realist tradition?
- Chronologically arrange the events in the Cold War period.
A. Berlin Wall is constructed
B. Communist China joins the UN
C. Soviet invasion of Czechoslovakia
D. Berlin Blockade
Choose the correct answer from the options given below: Morgenthau's principles of political realism are:
A. Politics is rooted in permanent and unchanging human nature which is basically self centred, self-regarding and self-interested
B. Politics is an autonomous sphere of action and cannot therefore be reduced to morals
C. International Politics is an arena of conflicting self-interests
D. The ethics of international relations is situational ethics which is very different from private morality
Choose the correct answer from the options given below:Who among the following political thinkers consider the anarchical self help system to be a compelling factor for States to maximise their relative power positions?
