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Question

Repeated sequence TTAGGC in humans is present at :
                                    AATCCG 

This question was previously asked in
CUET PG 2026 Agri-Business Management Question Paper (25-Mar-2026) (Shift 2)
The correct answer is
Telomere

Understanding Telomeres and DNA Repeats

Telomeres are specialized structures found at the ends of chromosomes in eukaryotic cells, including humans.

They consist of repetitive DNA sequences and associated proteins, serving a crucial protective role.

The main function of telomeres is to prevent the loss of genetic information during DNA replication and to protect chromosome ends from being recognized as DNA damage or undergoing fusion.

The TTAGGC Sequence Location

The question asks for the location of the repeated sequence 'TTAGGC' in humans. While the canonical human telomere repeat sequence is typically cited as 'TTAGGG', highly repetitive sequences are characteristic features of telomeres.

Given the options, the telomere is the known location for such specific, repetitive sequences that cap the ends of chromosomes.

Evaluating Other Options

  • Centromere: This is the region that connects sister chromatids and serves as the attachment point for spindle fibers during cell division. It contains different types of repetitive DNA sequences.
  • Nucleolus: This nuclear sub-organelle is primarily involved in ribosome biogenesis and contains ribosomal RNA genes, not the TTAGGC repeat.
  • Histones: These are proteins that help package DNA into structural units called nucleosomes. They are not DNA sequences themselves.

Final Identification

Therefore, the repeated sequence TTAGGC, characteristic of protective chromosome end structures, is found at the telomere.

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