Question
Which of the following classical disease-modifying anti-rheumatic drugs is/are considered safe for use during pregnancy? 1. Methotrexate 2. Sulfasalazine 3. Hydroxychloroquine 4. Leflunomide Select the correct answer using the code given below:
This question was previously asked in
UPSC CMS 2026 Surgery, Gynaecology & Obstetrics, and PSM Question Paper (02-Aug-2026)
The correct answer is
2 and 3
Methotrexate and Leflunomide are teratogenic and contraindicated in pregnancy, requiring discontinuation and washout before conception. Sulfasalazine and Hydroxychloroquine are considered safe DMARDs that can be continued during pregnancy.
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