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Question

Post-transplant lymphoproliferative disorder, a lymphoma that follows organ transplantation, is associated with infection with which one of the following?

This question was previously asked in
UPSC CMS 2026 Surgery, Gynaecology & Obstetrics, and PSM Question Paper (02-Aug-2026)
The correct answer is

Epstein-Barr virus

Post-transplant lymphoproliferative disorder (PTLD) is a B-cell lymphoproliferation driven by EBV infection in the setting of iatrogenic immunosuppression after solid organ or hematopoietic transplantation. EBV-transformed B cells proliferate unchecked when T-cell immune surveillance is suppressed.

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Important Questions from Viral Infections

  1. A 'slapped cheek' rash is characteristically seen in which of the following infections?
  2. HIV-associated neurocognitive disorder (HAND) includes which of the following? 

    1. Asymptomatic neurocognitive disorder 

    2. Minor neurocognitive disorder 

    3. HIV-associated dementia 

    Select the correct answer using the code given below.

  3. Which of the following treatments for a pregnant lady who has been exposed to a patient of chicken pox are correct? 

    1. Varicella-zoster immune globulin 

    2. Varicella-zoster vaccine 

    3. Acyclovir 

    4. Prednisolone 

    Select the correct answer using the code given below.

  4. Which of the following statements are correct regarding Kyasanur forest disease? 

    1. It is commonly seen in North-Eastern States of India. 

    2. Monkeys act as reservoir of the disease. 

    3. Transmission happens through tick bite. 

    4. Inactivated vaccine is available for its prevention. 

    Select the correct answer using the code given below.

  5. Which one of the following has the highest risk of human immunodeficiency virus (HIV) transmission after single exposure to an HIV-infected source ?
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