Neurofibrillary tangles and plaques are seen in brain scans of patients with :
Alzheimer’s disease
Extracellular amyloid (senile) plaques, made of beta-amyloid protein, and intracellular neurofibrillary tangles, made of hyperphosphorylated tau protein, are the two pathological hallmarks of Alzheimer’s disease, first described by Alois Alzheimer in 1906.
They accumulate first in the entorhinal cortex and hippocampus and then spread through the cortex, which explains the early memory loss and later global cognitive decline; PET imaging with amyloid and tau tracers can now visualise them in living patients.
Traumatic brain injury shows contusions, haemorrhage and diffuse axonal injury; temporal lobe epilepsy is typically linked with hippocampal sclerosis; meningitis is inflammation of the meninges due to infection.
Hence, the answer is Alzheimer’s disease.
Similar Questions
Resting membrane potential is :
Which among the following is the chief inhibiting neurotransmitter ?
Match List I with List II and select the correct answer using the codes given below :
List I List II (a) Hypothalamus (1) Causes extreme over-eating (b) Lateral hypothalamic damage (2) Responsible for monitoring food intake (c) Ventromedial hypothalamic damage (3) Regulate feeling of hunger (d) Changes in levels of Glucose (4) Leads to refusal of food and starvation Codes :
(a) (b) (c) (d)
Agnosia is an inability to :
Match List I with List II and select the correct answer using the codes given below :
List I (Traditional Terms) List II (Structures) (a) Telencephalon (1) Cerebellum (b) Diencephalon (2) Tectum (c) Mesencephalon (3) Cerebral cortex (d) Metencephalon (4) Thalamus Codes :
(a) (b) (c) (d)
Which is odd among the following for HIV ?
Lumber punctures can be used to diagnose :
(1) Bacterial meningitis
(2) Viral infections
(3) Brain abcess and tumor
(4) Multiple sclerosis
Unmyelinated intervals on axons are called :
The term psychoneuroimmunology is associated with which of the following ?
Match List I with List II and select the correct answer using the codes given below :
List I (Brain area) List II (Function) (a) Broca area (1) Non-reflexive movement (b) Wernicke area (2) Speech production (c) PFC (3) Planning and organization (d) Primary motor cortex (4) Speech comprehension Codes :
(a) (b) (c) (d)
Important Questions from Human body
- Which of the following minerals is essential for oxygen transport in the blood?
- How many pairs of false ribs are located above the floating ribs that are connected to each other by costal cartilage?
- Which mineral helps in the formation of insulin granules, digestion, metabolism and functioning of the male prostate?
- Which of these nutrients is the main energy source for the body/ human diet?
Consider the following statements regarding diabetes:
1. It is caused by the oversecretion of insulin by pancreas.
2. The glucose level increases in the blood.
3. The patient urinates frequently, loses weight and becomes lethargic.
How many of the statements given above are correct?
