In a historical study, the death rate among heavy smokers was 224 per 1 lakh person-years while among non-smokers was 10 per 1 lakh person-years. The death rate in the general population was 74 per 1 lakh person-years. Which one among the following best represents the attributable risk of smoking for mortality in the given scenario?
95.5%
The correct answer is 95.5%. Attributable risk percent among the exposed = [(Incidence in exposed − Incidence in non-exposed) ÷ Incidence in exposed] × 100. Substituting: incidence in heavy smokers = 224 and in non-smokers = 10 per 100000 person-years. Excess risk = 224 − 10 = 214 per 100000 person-years. AR% = (214 ÷ 224) × 100 = 95.5% — that is, about 95.5% of deaths in heavy smokers are due to smoking. (Relative risk here = 224/10 = 22.4.)
Why the others are wrong: 22.4% misreads the relative risk of 22.4 as a percentage. 86.5% comes from wrongly using the general-population rate as denominator: (74 − 10)/74 = 86.5%, which is the population attributable risk percent, not AR in the exposed. 67.0% corresponds to no valid calculation; the figure of 74 is a deliberate distractor.
Key point: AR% uses the exposed group as denominator; PAR% uses the total population rate. The denominator alone separates these two answers.
In a given set of conditions, a screening test has 90% sensitivity and 90% specificity for screening a particular disease. The prevalence of the disease at the given time in that population is 10%. Which one of the following statements regarding positive predictive value of the test is correct?
In a given population of 10000, there were 30 cases of diabetes already present on 01/01/2025 and in the year 2025, 400 more cases developed diabetes. But 10 cases of diabetes died in the year 2025, i.e., before 31/12/2025. Which one of the following statements is correct regarding the disease situation?
The parameter which provides an estimate of the amount by which the disease under study can be reduced in a population, if the suspected factor is eliminated from that population, is called
Which one of the following statements regarding sample registration system is not correct?
What is the specificity of sputum microscopy in detection of Pulmonary Tuberculosis (PTB) as per the information given below?
| PTB | Total | ||
| Sputum microscopy | Present | Absent | |
| Positive | 270 | 20 | 290 |
| Negative | 30 | 180 | 210 |
| Total | 300 | 200 | 500 |
In a cohort of 500 women attending antenatal clinic, 70 % had ultrasonography (USG). This cohort was followed up at delivery. Of the women who had USG, 70 delivered low birth weight (LBW) babies; whereas of the women, who did not undergo USG, 50 delivered LBW babies. The incidence of LBW babies among women who had USG is:
In a case-control study, 300 women aged 20-45 years suffering from breast cancer were compared with age-matched 300 women without breast cancer. It was observed that 120 women among cases and 60 women among controls were obese. The odds ratio of developing breast cancer among obese women is:
What is the relative risk of developing pulmonary embolism in users of oral contraceptives as per the information given below?
| Women using OCs | Pulmonary embolism | Total | |
| Yes | No | ||
| Yes | 120 | 80 | 200 |
| No | 10 | 70 | 80 |
| Total | 130 | 150 | 280 |
Which one of the following tests should be applied to compare mean haemoglobin level of two groups of antenatal mothers?