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Question

Which one of the following air pollutants combine with the haemoglobin of human blood and reduces its oxygen-carrying capacity, leading to suffocation and may cause even death?

This question was previously asked in
CDS I 2016 English Previous Year Paper (14-Feb-2016)
The correct answer is

Carbon monoxide

Understanding Air Pollutants and Their Impact on Health

Air pollution poses significant health risks, affecting various systems in the human body. The question asks about a specific air pollutant that interferes with the blood's ability to carry oxygen by binding to hemoglobin. Let's examine the options provided:

  • Chlorofluorocarbon (CFC)
  • Fly ash
  • Carbon monoxide
  • Sulphur dioxide

Analyzing the Impact of Each Pollutant

We need to identify which of these substances directly binds to hemoglobin, the protein in red blood cells responsible for transporting oxygen.

1. Chlorofluorocarbon (CFC): CFCs are chemicals primarily known for their role in depleting the stratospheric ozone layer. While they are air pollutants and can have some health effects, their main impact is not through direct binding with hemoglobin and reducing oxygen transport in the blood.

2. Fly ash: Fly ash consists of fine particles produced during the combustion of coal. It is a major component of particulate matter air pollution. Inhaling fly ash can cause respiratory problems, lung damage, and cardiovascular issues, but it does not directly bind to hemoglobin in the way described in the question.

3. Carbon monoxide (CO): Carbon monoxide is a colorless, odorless, and toxic gas produced by the incomplete combustion of carbon-containing fuels. When inhaled, CO readily passes from the lungs into the bloodstream. Its structure is similar enough to oxygen (\(O_2\)) that it can bind to the same site on the hemoglobin molecule.

  • Carbon monoxide has an affinity for hemoglobin that is about 200-250 times stronger than that of oxygen.
  • When CO binds to hemoglobin, it forms a complex called carboxyhemoglobin (COHb). The reaction can be represented as: \(Hb + CO \rightarrow HbCO\) (where Hb is hemoglobin).
  • The formation of COHb significantly reduces the amount of hemoglobin available to carry oxygen.
  • This leads to oxygen deprivation in tissues and organs, a condition known as hypoxia.

Symptoms of carbon monoxide poisoning range from headache, dizziness, and nausea in mild cases to confusion, loss of consciousness, suffocation, and ultimately death in severe cases.

4. Sulphur dioxide (SO₂): Sulphur dioxide is a toxic gas produced mainly from the burning of fossil fuels containing sulphur, such as coal and oil. SO₂ is a major contributor to acid rain and respiratory problems like asthma and bronchitis. While it is a harmful air pollutant affecting the respiratory system, it does not bind to hemoglobin in the blood to significantly reduce oxygen transport in the manner that carbon monoxide does.

Conclusion

Based on the analysis, carbon monoxide is the air pollutant among the given options that binds strongly to hemoglobin, forming carboxyhemoglobin, which reduces the blood's oxygen-carrying capacity. This reduction in oxygen transport can lead to suffocation and death.

Pollutant Primary Health Impact Related to Question Hemoglobin Binding?
Chlorofluorocarbon (CFC) Ozone depletion, some health effects No significant direct binding
Fly ash Respiratory & cardiovascular issues (particulate) No significant direct binding
Carbon monoxide (CO) Oxygen deprivation (hypoxia), suffocation, death Yes, strong binding (HbCO)
Sulphur dioxide (SO₂) Respiratory irritation, acid rain effects No significant direct binding

Revision Table: Key Air Pollutants and Effects

Air Pollutant Main Source(s) Key Health Effect(s)
Carbon Monoxide (CO) Incomplete combustion (vehicles, furnaces, fires) Reduces blood's oxygen capacity, affects heart & brain
Sulphur Dioxide (SO₂) Burning fossil fuels (power plants, industry) Respiratory problems, acid rain
Nitrogen Oxides (NOx) Combustion (vehicles, power plants) Respiratory problems, smog formation, acid rain
Particulate Matter (PM) Combustion, dust, industrial processes Respiratory & cardiovascular problems, lung damage
Ozone (\(O_3\)) Formed from NOx and VOCs in sunlight Respiratory problems, lung damage

Additional Information on Carbon Monoxide Poisoning

Carbon monoxide is particularly dangerous because it is undetectable by human senses. It often results from faulty heating systems, car exhaust in enclosed spaces, or poorly ventilated fires. The effects of carbon monoxide poisoning depend on the concentration of CO in the air and the duration of exposure.

  • Even low concentrations of CO can cause health problems over time.
  • High concentrations can be fatal within minutes.
  • Smokers have higher baseline levels of carboxyhemoglobin due to CO in cigarette smoke.
  • Individuals with heart disease, respiratory problems, infants, and the elderly are more vulnerable to the effects of carbon monoxide.

Preventing carbon monoxide poisoning involves ensuring proper ventilation, regular maintenance of combustion appliances, and using CO detectors in homes and workplaces.

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