Question
The correct sequence of transmission of pain/nociceptive stimulus from distal to proximal is : A. Lateral spinothalamic tract B. Transmission cells or T cells/Interneurons C. Third order neuron D. Dorsal root E. Cerebral cortex Choose the correct answer from the options given below :
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CUET PG 2026 Agri-Business Management Question Paper (25-Mar-2026) (Shift 2)
The correct answer is
D, B, A, C, E
Understanding Pain Stimulus Transmission
The question asks to identify the correct sequence for the transmission of a pain or nociceptive stimulus, moving from the periphery (distal) towards the central nervous system and brain (proximal).
Tracing the Nociceptive Pathway
The pathway involves several key structures and neuronal components:
- Dorsal root (D): This is where sensory nerve fibers, carrying the initial stimulus from the periphery, enter the spinal cord.
- Transmission cells or T cells/Interneurons (B): Within the dorsal horn of the spinal cord, the primary sensory neuron synapses with secondary neurons. These are often transmission cells or interneurons that process and relay the signal.
- Lateral spinothalamic tract (A): The secondary neurons typically cross to the opposite side of the spinal cord and ascend towards the brain via the lateral spinothalamic tract, a major pathway for pain and temperature.
- Third order neuron (C): Neurons originating in the thalamus (a relay station in the brain) form the third-order neurons. These project from the thalamus to the cerebral cortex.
- Cerebral cortex (E): This is the final destination where the pain stimulus is consciously perceived and interpreted.
Sequencing the Neural Transmission
Following the path from distal to proximal:
- The stimulus enters the spinal cord via the Dorsal root (D).
- It synapses with Transmission cells/Interneurons (B) in the spinal cord.
- The signal ascends via the Lateral spinothalamic tract (A).
- From the thalamus, the Third order neuron (C) carries the signal further.
- The signal reaches the Cerebral cortex (E) for perception.
Therefore, the correct sequence is D, B, A, C, E.
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