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Question

Progression of the disease leads to degeneration of neurons and presence of Cytoplasmic inclusion bodies, called Lewy bodies. This is seen in which disease of the nervous system ?

This question was previously asked in
CUET PG 2026 Agri-Business Management Question Paper (25-Mar-2026) (Shift 2)
The correct answer is
Parkinson's Disease

Understanding Disease Progression and Pathological Markers

The question highlights two critical pathological features associated with a progressive nervous system disease: degeneration of neurons and the presence of specific cellular structures called cytoplasmic inclusion bodies, explicitly named Lewy bodies.

Identifying the Specific Neurological Condition

Lewy bodies are abnormal accumulations of protein that disrupt normal brain function. Their identification within degenerating neurons is a key diagnostic hallmark.

Specifically, the combination of neuronal degeneration and the presence of Lewy bodies is pathognomonic for Parkinson's Disease. This pathology is central to the development of the characteristic motor symptoms seen in Parkinson's patients.

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